interaction of chloroacetamide electrophiles with cellular glutathion

interaction of chloroacetamide electrophiles with cellular glutathion Transduction Redox Signaling by Electrophile-Protein Reactions Application of a MALDI mass

Name: interaction of chloroacetamide electrophiles with cellular glutathion Transduction Redox Signaling by Electrophile-Protein Reactions Application of a MALDI mass
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Application of a MALDI mass spectrometry assay to identify covalent fragments targeting the methyl lysine reader protein MPP8 SLAS Discovery Sulfamate Acetamides as Self Immolative Electrophiles for Covalent Ligand Directed Release Chemistry Journal of the American Chemical Society Formation of protein derived electrophiles in ribonuclease A by biologically relevant oxidants ScienceDirect Electrophilic compound screening identifies GPX4 dependent ferroptosis as a senescence vulnerability Nature Cell Biology

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References Kelland, L

Biochimie 136:7584

All 16 samples were loaded into hydrophilic capillary tubes for 30 min before the final measurements were taken in a Monolith NT.115 instrument (Nanotemper, Munich, Germany)