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Interestingly, GPx7 and ERO1 can interact with PDI simultaneously, with ERO1 oxidizing the a domain of PDI, and generating H 2 O 2 that is subsequently used by GPx7 to oxidize the a domain (Wang et al., 2014)

Molybdenum Helps enzymes that process sulfur compounds and aldehydes, including acetaldehyde (source, source)

ER stress arises when there is imbalance between the load of ER client proteins that must be processed and the ability of the organelle to properly process them