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In animals, pigs with RF deficiencies have decreased growth performance and less appetite

Low levels of B12 can cause fatigue, nervousness, dizziness, numbness, and tingling in the fingers and toes

J Diabetes Investig (2019) 10(3):699705

They both involve oxidative stress and inflammation in their progression, which has led to the coining of the term "diabetes encephalopathy" or "type 3 diabetes" (T3DM) [76,77,78]