how does glutathione s-transferase cause drug resistance in cancer cells

how does glutathione s-transferase cause drug resistance in cancer cells The multifaceted role of S-transferases Unveiling the mechanisms and challenges

Name: how does glutathione s-transferase cause drug resistance in cancer cells The multifaceted role of S-transferases Unveiling the mechanisms and challenges
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Unveiling the mechanisms and challenges of cancer drug resistance Cell Communication and Signaling Springer Nature Link Frontiers Glutamine's double edged sword: fueling tumor growth and offering therapeutic hope Glutathione S transferase Theta 2 causes drug resistance by inhibiting arsenic trioxide induced ferroptosis in pancreatic ductal adenocarcinoma ScienceDirect Glutathione transferases: substrates, inihibitors and pro drugs in cancer and neurodegenerative diseases Oncogenesis

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These discrepancies may be attributed to variations in study design, sample size, and trial standards

Clinical trials indicate that IVC does not adversely interfere with chemotherapy and pre-clinical studies indicate that it may in fact act synergistically in combination with different chemotherapeutic agents