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Researchers couldnt make the IGF-diabetes association in people over age 65 Better Heart Health In 15-years prospective study of 231 cases and 374 matched controls without any sign of ischemic heart disease (IHD) at the baseline of the study, those with baseline IGF-I levels in the lowest quartile had a 2-fold increased risk of IHD (when the major IGF-binding protein, IGFBP-3, was controlled)

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Wolfram J, Zhu M, Yang Y, Shen J, Gentile E, Paolino D, et al

Recent advances in single-molecule DNA and multiplexed ribosomal RNA fluorescence in situ hybridization (FISH) have enabled mapping and visualization of taxa and mobile genetic elements in human plaque biofilms, however, there have yet to be analogous studies on biofilms in the vaginal microbiome 57,58