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On the other hand, moderate hyperhomocysteinemia induces immune activation through ROS and oxidative stress (Schroecksnadel et al

Many commonly studied ingredients such as vitamin C, glutathione precursors, niacinamide, and plant polyphenols have established safety data when taken within recommended ranges

In an OGD/R-induced BV2 cell injury model, lobetyolin significantly inhibited the secretion of proinflammatory factors, such as TNF- and IL-6, downregulated the expression of inducible nitric oxide synthase (iNOS), and facilitated the M1-to-M2 phenotypic switch, thereby mitigating neuroinflammatory damage (Wang J

the body converts a large proportion of it back into the active GSH form