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PLoS One 2014;9:e110002.ArticlePubMedPMC 194

The level of cytosolic accumulation is then inferred from the fluorescence signal produced by a chloroalkane-fluorophore chase molecule

A recent report documented accumulation of the ceramide precursor sphingosine and C20:0, C22:0, C22:1, C24:0 and C24:1 ceramide species in mitochondria isolated from both 5xFAD mice and AD patient brains (Crivelli et al., 2024)