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Statements Author contributions MF: Conceptualization, Data curation, Methodology, Validation, Writing original draft

The presence of ZnT8A, as well as IA-2A and ZnT8A positivity, can identify individuals with prediabetes who are at a high risk of rapidly progressing to clinical type 1 diabetes

Oxidative stress and signaling disruption increase neuronal vulnerability to inflammation and promote excess neurotoxic amyloid- peptides, which are key in the pathology of Alzheimers disease (AD) pathology (172)