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1500-C HBsAg LOSS DURABILITY AND RATES OF HBsAg SEROREVERSION IN PATIENTS WITH CHRONIC HBV INFECTION, A SYSTEMATIC LITERATURE REVIEW Vera Gielen 1 , Supriya Desai 2 , Mounika Adepu 2 , Shayon Salehi 1 and Anadi Mahajan 2 , (1)GSK, Brentford, UK, (2)Bridge Medical Consulting, London, UK Background: Functional cure, defined as hepatitis B surface antigen (HBsAg) and HBV DNA undetectable after completion of all treatment, is regarded as the elevated treatment endpoint for patients with chronic HBV (CHB) infection, but is rarely achieved