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67,179 This second phase of acute focal TBI is complete about a month after the insult, when the mature lesion, composed of the central fibrotic scar (fully devoid of neural elements) and the surrounding astroglial limitans border have formed

Via high-butyrate diet intervention and adoptive transfer experiments, it confirmed that a high-butyrate diet can induce the differentiation of follicular Tregs through HDAC inhibition, suppress the production of type II collagen (CII)-specific autoantibodies, and reduce joint swelling and bone erosion