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Untreated CD1 mice subjected to TBI displayed ample evidence of a primary mechanical injury, including regions of BBB disruption detected by MRI, alterations in Tau phosphorylation and expression, and substantial increases in righting reflex times and apnea, in comparison to Sham control mice

The weight loss stalling that many patients experience during semaglutide therapy can also be partially attributed to declining lean mass and the metabolic slowdown it causes

Several metabolitemetabolite associations across the tyrosine, tryptophan, and purine pathways were found to be changed as a function of higher or lower outcome status (Supplemental Table 5 A, B)

& Adisakwattana, S