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Baseline metabolites were compared between the following groups: (1) Dogs with DCM eating NT diets (DCM-NT) + dogs with DCM eating T diets (DCM-T)] were compared to healthy control dogs eating NT diets (C-NT) + healthy control dogs eating T diets (C-T) and (2) Dogs eating NT diets (DCM-NT + C-NT) were compared to dogs eating T diets (DCM-T + C-T)

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To change monocyte and reprogram immune cells' metabolism to a pro-inflammatory situation, they used a nanoparticle approach to deliver the oligomycin, an inhibitor of OxPhos, to monocyte cells (Yamada et al