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Additionally, rhamnetin disrupts the cleavage of the Notch-1 receptor by gamma-secretase, preventing the release of the Notch intracellular domain (NICD)

Grellier P, Marozien A, Nivinskas H et al (2010) Antiplasmodial activity of quinones: roles of aziridinyl substituents and the inhibition of Plasmodium falciparum glutathione reductase