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Earlier studies proposed that macroautophagy, regulated by p62, is accompanied by increased activity of most HSP70s (Sheng et al., 2012)

In early 1980s, Richard Morris, a researcher studying spatial navigation in rats, developed a new kind of test for spatial memory, which he published in 1984 under the title "Developments of a water-maze procedure for studying spatial learning in the rat" (7)