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Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX), a producer of reactive oxygen species (ROS), acts as a key generator of oxidative stress within pancreatic islet -cells, significantly affecting glucose-induced insulin release and -cell viability in Type 1 and Type 2 diabetes (Marta et al., 2010)

Using the same cohorts and similar modeling, a lower risk of RA was also observed with a healthier lifestyle, i.e., women with five healthy lifestyle factors had the lowest risk (HR 0.42 [95%CI: 0.22-0.80]) (54)

Therefore, future research should further explore the potential application value of CLA in pulmonary infections and inflammatory diseases, which could facilitate the development of novel CLA-based therapeutic strategies

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