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425,426 Aging, smoking, cardiovascular disease, obesity, high-fat diet, hypertension, excessive sun exposure, and other factors can induce mtDNA damage and increase ROS production, resulting in mitochondrial dysfunction and ultimately leading to RPE cell damage

Moreover, specific strains of bacteria have been shown to modulate behavior when administered to animals, suggesting a causal role for certain microbial populations in emotional and cognitive processes (Savignac et al., 2014

The samples were centrifuged at 10000 g, 4C for 10 min and the absorbance was measured by spectrophotometer (UV-5500, Shanghai Chemical Laboratory Equipment Co., Ltd., Beijing, China) at wavelengths 470, 646 and 663 nm

Glutathione has also been used to treat Parkinsons disease, sickle cell anemia, idiopathic pulmonary fibrosis, and poisoning, as it can detoxify the body of heavy metals such as mercury