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Targeting the JAM3-NRF2/FSP1 pathway presents a promising therapeutic strategy to overcome drug resistance and increase ferroptosis sensitivity (102).Additionally, Frizzled-7 (FZD7) is a key marker of platinum-resistant OC cells (103, 104)

& Lewin, J

miR126 overexpression attenuates oxygenglucose deprivation/reperfusion injury by inhibiting oxidative stress and inflammatory response via the activation of SIRT1/Nrf2 signaling pathway in human umbilical vein endothelial cells