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Description

Reduction of proinflammatory effector functions through remodeling of fatty acid metabolism in CD8+ T cells from rheumatoid arthritis patients

H.HuangY.LiaoX

This hyperestrogenic state is frequently accompanied by the downregulation of androgen receptor (AR) expression, causing a severe imbalance in the estrogen/androgen receptor (ER/AR) ratio (103, 105), which subsequently disrupts Sertoli cell function and ultimately inhibits sperm development and capacitation (104)