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Krasemann et al., 2017), and monocyte-derived TREM2-expressing disease inflammatory macrophages (DIM

Due to the increased amount of adipose tissue, obese patients are more predisposed to systemic inflammation with higher levels of pro-inflammatory cytokines, such as interleukin 6, eotaxin-1, TNF-, transforming growth factor beta 1 (TGF-1) and CRP

517 At weeks 0, 2, and 6, patients treated with 300 mg of vedolizumab experienced significant clinical remission and mucosal healing, with significant reductions in symptoms such as rectal bleeding

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