melanotic mucosa in colon Melanosis coli Melanosis coli is dark brown-black

Material was then dissolved in DMEM, and diluted to a final volume of 25 ml with DMEM

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2.2 Transcriptional regulatory networks 2.2.1 Epigenetic dominance of the TOX/NR4A family In the fate determination of exhausted T cells, the transcription factors of the TOX and NR4A families serve as masterminds, reshaping the gene expression profile of T cells through epigenetic regulation, gradually plunging them into the quagmire of exhaustion (112, 113)

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