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From June 2017 to June 2019, researchers evaluated the safety and efficacy of CAR-T cell immunotherapy targeting Mesothelin, PSCA, CEA, HER2, MUC1, and EGFRvIII for pancreatic cancer

Pharmacokinetic (PK) profiling in both species revealed linear doseexposure relationships, with [H] BPC157 rapidly metabolized into small peptides and ultimately tritium-labeled proline for normal amino acid catabolism/excretion [11]