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Blood 139 , 584596 (2022)

10.1126/scitranslmed.aax0876 Sci Transl Med

Plasma obtained from healthy adults following a single 300 mg oral dose of PYC induced pronounced apoptotic cell death in human fibrosarcoma (HT1080) cells, whereas plasma from untreated individuals showed no such effect ( Beyond direct induction of apoptosis, PYC modulates key molecular pathways involved in cancer cell survival and migration