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Chorioamnionitis, a devastating infection with increased risk of cerebral palsy and other neurological sequalae, may benefit from intravenous NAC (both antenatally and postnatally) by reducing neuroinflammation [74]

Cellular senescence Evolutionary considerations suggest aging is caused not by active gene programming but by evolved limitations in somatic maintenance, resulting in a build-up of damage. (Kirkwood, 2005) In this section, we will discuss important notions in cellular senescence and highlight selected recent findings, related to glial heterogeneity and disease association

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We are also grateful for the support of the Woolcock Institute of Medical Research and Flinders University sleep centre where this research was conducted