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(c) nuclear translocation of predominantly p65/p50 dimers to induce transcription of target genes, including well-established FLICE-like inhibitory protein (c-FLIP) and apoptosis protein inhibitors (c-IAP)

Although -glutamyl-peptides per se did not directly protect cells against ferroptosis under cystine starvation, their biosynthesis consumes glutamate, an intracellular amino acid that was previously implied in ferroptosis induction via glutaminolysis 13

5-oxo-DL-Proline (6.21%)

reported that HGSC tumors are driven predominantly by TDO2 in promoting tumor progression and immune evasion via kynurenine (KYN) production