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That decline shows up as stubborn body fat, poor sleep, slow recovery, and thinning skin

noted reduced expression of the GHR in the kidneys of 5/6 nephrectomized animals, which was associated with elevated pro-inflammatory cytokines, suggesting that GH-insensitivity in uremia is a general phenomenon and not restricted to the liver and growth plates ( vide supra ) [174]

[DOI] [PubMed] [Google Scholar] 177.Miller SB, Moulton M, O'Shea M, Hammerman MR

It stands out among growth hormone releasing peptides for its unique property of not activating the bodys stress response, a common effect in other compounds of its class