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Description

Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor-1 stabilization

113 NeffRLFarrarWBKloosRTBurmanKD

suis, Rachel Kanefsky, Allyson Dailey, Dr

This severe depletion of GSH results in the synthesis of large amounts of -glutamylcysteine, which is increasingly converted to pyroglutamate when glycine is depleted, leading to metabolic acidosis