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Urinary concentrations of 15-epimer of lipoxin A 4 are lower in patients with aspirin-intolerant compared with aspirin-tolerant asthma

However, comprehensive analyses integrating transcriptome-metabolome-and microbiome data remain an area needing further exploration

In the treatment of breast cancer, anti-estrogen tamoxifen, the drug most often used for the long-term treatment of early breast cancer, can induce apoptosis in many cells, and this effect may be mediated by ROS generation in the mitochondria of breast cancer cells [71]

Patients should also be aware of potential side effects, which may include local irritation or allergic reactions, although these are generally rare