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Description

SVCT1 is found mostly in epithelial tissues (e.g., small intestine and proximal tubule of the nephron), where the transport of ascorbate is greater than that required by the cells

This allowed a variety of boronic acids to be coupled to a model cysteine-linked aryl iodide, with the benefit that even hydrophobic moieties could be transferred to the protein surface due to the water-solubilizing effect of the boronate group