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It shifts melanin production away from darker eumelanin toward lighter phaeomelanin

10.3892/etm.2019.7311 82 HalliwellB.CheahI

[13] Trials for obesity [edit] In March 2021, in a phase III randomized, double-blind trial, 1,961 adults with a body mass index of 30 or greater were assigned in a 2:1 ratio to a treatment with once-weekly subcutaneous semaglutide or placebo, plus lifestyle intervention