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19,67,73,74 Newly proliferated reactive astrocytes form borders that separate damaged, inflamed, and fibrotic tissue from adjacent viable neural tissue, and during this border formation newly proliferated astrocytes become transcriptionally reprogrammed to adopt new cellular interactions with non-neural cells

Curhan SG, Eavey RD, Wang M, Rimm EB, Curhan GC

Our investigation into TUDCA supplements began by examining the compounds biological role and clinical use

The alteration of the gut microbiome ultimately results in the alleviation of neuroinflammation and neurodegenerative diseases by affecting physiological processes such as immune cell development and migration, amyloid deposition, BDNF and NMDA signaling (218220)