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Because serum alanine aminotransferase (ALT) levels have been reported to predict the histological course of NASH and because strict control of ALT is required to prevent the progression of NASH [13], the primary outcome of this study was a change in ALT levels

Table 3 presents the patients satisfaction regarding the effectiveness of NAC at 12 weeks of treatment

Acta Cir Bras 33:508517

Inflammation Induction of inflammatory responses in the glomerulus, renal tubular cells, and the surrounding interstitium is another mechanism of drug-induced nephrotoxicity that can lead to fibrosis and renal scarring (Naughton 2008b)