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Yet, as with NRF2, tumor contexts complicate interpretation: HO-1 is overexpressed in some cancers, including HCC, where it actively supports tumor progression by enhancing survival via mechanisms such as increasing cancer cell proliferation, conferring resistance to chemo- and radiotherapy, and promoting angiogenesis, as indicated by its strong correlation with VEGF expression and microvascular invasion

The following sub-sections discuss the most common modes of action of EDCs in affecting human reproductive health

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A Pt-deposited NGODs:GO catalyst exhibited stable H production for 96 hours with a quantum yield of 16.0%, significantly outperforming NGODs alone, which showed a 50% activity decline over the same period