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coli strains BL21(DE3), B and K12 served as a control

Research suggests that L-citrulline is most effective at doses of at least 3 grams per day, with optimal benefits closer to 8 grams

In addition, it is free from GMOs, nuts, gluten, lactose and wheat

Firstly, conduct high-throughput screening and preclinical validation of saponin-chemotherapeutic drug pairs across different tumor types, to identify optimal combinations that achieve mechanistic complementarity by targeting the inherent limitations of chemotherapeutic agents (e.g., drug resistance, off-target toxicity) and establish a standardized database for rational regimen design