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By reducing NNMT catalytic activity, the compound allows researchers to evaluate how limiting nicotinamide methylation influences: In vitro and in vivo experimental models (non-clinical, non-human) have demonstrated that NNMT suppression leads to measurable changes in cellular energy markers and adipocyte behavior

Engstrm W, Zetterberg A (1983) Phosphate and the regulation of DNA replication in normal and virus-transformed 3T3 cells

10.1016/j.biotechadv.2011.08.007 54 GeorgievV.SlavovA.VasilevaI.PavlovA