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Interestingly, a new sight against hepatotoxicity may be to promote the stress activation of Nrf2 (Jia et al., 2019

Consequences of oxidative stress Oxidative attack by ROS is manifested as damage to nucleic acid bases, lipids and proteins, which can severely compromise cell health and viability or induce a variety of cellular responses through the generation of secondary reactive species, ultimately leading to cell death by necrosis or apoptosis [48]