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10.3390/curroncol28030193 91 XuZ.LuoW.ChenL.ZhuangZ.YangD.QianJ.et al (2022)

4) The PI3K/Akt/mTOR pathway represents a central survival signaling axis in ischemic AKI, regulating cell proliferation, apoptosis, oxidative stress responses, and autophagy

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The good news is that the treatment for B12 deficiency is to take over-the-counter B12 supplements (or B12 shots which we will discuss below) and the problem is typically rapidly addressed