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doi:10.1093/advances/nmz013 Mailoo VJ, Rampes S

Key findings include: Reduced anxiety behaviors in BALB/c mice at 100-300 mcg/kg doses Strain-specific effects with pronounced activity in high-anxiety mouse strains Anxiolytic potency comparable to diazepam without sedative effects Enhanced efficacy in combination with low-dose benzodiazepines Research in chronic unpredictable mild stress models showed that Selank (50 mcg/kg daily) prevented stress-induced behavioral deterioration and maintained baseline anxiety indicators comparable to pre-stress levels