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Additionally, autophagy plays an important role in CRPC [43, 44], and -ketoglutarate generated by glutamine metabolism functions via the TCA cycle and synthesizes biological macromolecules and acts as a cofactor for the histone demethylases JmjC-KDMs and members of the DNA demethylase TET family, participating in promoting histone and DNA demethylation processes and regulating gene expression [45]

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construct a bimetallic metal-organic framework (Pt@ZIF-8@La), which efficient scavenging of ROS and promote osteogenic mineralization by upregulating the ratio of the osteprotegerin/receptor activator of the NF-B ligand to osteogenesis [121]

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Automaticity is the ability of the heart muscle cells to generate an electrical impulse

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