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The levels of HYP, -SMA, and collagen I were significantly decreased in the Lysionotin-treated group compared to the BLM model group

Affected patients classically develop massive proteinuria, nephrotic syndrome, and rapid progression to end-stage renal disease, most commonly in the setting of HIV infection, parvovirus B19, or severe COVID-19

Incorporating immune and stromal cell into co-culture systems increases their biological significance, while OOC platforms and bioprinting technologies replicate dynamic physiological settings, facilitating HTS drug screening and tailored therapeutic approaches

Clear records help track preparation methods across different staff members