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Contemporary biological theories are broadly categorised into programmed theories and damage- or error-based theories

Symptoms include: Fatigue and weakness Chronic burning in the throat and nasal passages Coughing, wheezing, and shortness of breath Loss of balance Depression and anxiety Skin rashes Eye irritation or tearing of the eyes Headache and light sensitivity Hearing loss Heightened sensitivity to chemicals and foods Irregular heartbeat Morning stiffness and joint pain Muscle weakness Sleep problems Poor memory, difficulty finding words Slower reaction time Vision changes Difficulty concentrating Abdominal pain, diarrhea, and bloating Unusual skin sensations, tingling, and numbness Increased urinary frequency or increased thirst Disorientation and dizziness Static shocks or metallic taste in the mouth Additionally, mycotoxin toxicity is linked explicitly to neurological symptoms, with cognitive, emotional, and behavioral effects

In 2023 it was reported that the aging pigment lipofuscin can be broken down with the help of melanin and drugs through a newly discovered mechanism

PLoS One 2021;16:e0254590