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Our results are the first to demonstrate an association between urine GPX4 levels and anemia in cats with CKD, although the underlying mechanism remains unclear

SLC7A11, a key FRG in pan-RCC and a major functional subunit of the system X c , which participates in cysteine transport and inhibits cellular ferroptosis by participating in GSH synthesis, seems to have opposite effects on the regulation of disulfidptosis and ferroptosis, and further exploration of both of these effects is needed (185)

their role in tumorigenesis, metastasis, prognosis and therapy