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SKU: 37461847256 · From webdevsolutions.tech

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Description

Indomethacin had a limited therapeutic effect on the reduction of pro-inflammatory and pro-apoptotic markers compared to BCSO and its nanoemulsion formulation

Unlike -KG, abnormal accumulation of succinate and fumarate in tumor tissues represses PHD, thus reducing HIF1 hydrolysis, suppressing demethylation of DNA and histones, and promoting the occurrence and development of tumors (Cavalli and Heard, 2009