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Current investigations are focused on understanding whether NNMT inhibition might influence cancer progression or aggressiveness

The applicant also asserted that CMS's literal application of its example that a pacemaker is integral to the procedure of implantation of a pacemaker is overly simplistic and suggests that any feature beyond the basic function of a device could be considered non-integral. In addition, the applicant asserted that CMS has previously deviated from this approach when determining transitional pass-through payment status