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Niraparib showed promising activity in preclinical models and phase I clinical trials, achieving its pharmacodynamic target for PARP inhibition in epithelial ovarian cancer, particularly in patients who have responded to platinum-based chemotherapy 167 (Fig

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A multicenter RCT (n=83), however, found no significant differences between glutathione supplementation and placebo.54 Oral Melatonin Melatonin is a hormone secreted by the pineal gland, but it is also synthesized and metabolized in the skin