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Koppe T, Patchen B, Cheng A, Bhasin M, Vulpe C, Schwartz RE, Moreno-navarrete JM, Fernandez-real JM, Pissios P, Fraenkel PG (2017) Nicotinamide N -methyltransferase expression decreases in iron overload, exacerbating toxicity in mouse hepatocytes

188,189 Even when in situ vaccination activates tumor-specific T cells, their antitumor activity is quickly suppressed upon re-entry into the TME, leading to functional exhaustion and immune failure

Acetatifactor relative abundance was greater in 5A-1MQ-treated mice switched from WD to LD compared to WD (without FDR correction) and LD controls (Supplementary Fig