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In parallel, causal in vivo studies targeting key structural regulators of these contact sites, such as MFN2 and other tethering proteins, will be particularly informative for determining whether disruption of organelle interaction hubs directly contributes to mitochondrial dysfunction, metabolic imbalance, and functional ovarian decline

(b) a low serum concentration of vitamin B12 with a normal folate concentration

Role of MRP transporters in regulating antimicrobial drug inefficacy and oxidative stress-induced pathogenesis during HIV-1 and TB infections