ROS are implicated in the pathogenesis of acute and chronic peptic ulceration being detrimental to the integrity of the gastroduodenal mucosa and more crucial than acid hypersecretion in this respect [17]
doi: 10.1186/s43897-023-00059-y Summary Keywords flavonoid biosynthesis, transcriptional regulation, plant cell factory, metabolic engineering, artificial intelligence Citation Wang Y, Chen J, He G, Yin L and Liao Y (2025) Unlocking the potential of flavonoid biosynthesis through integrated metabolic engineering

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This study further demonstrates the potential of KO to be applied in topical formulations as it can overcome issues related to oral formulations, which is biodistribution and metabolic transformation, and directly target keratinocytes (110)