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Although immunogenicity to biologics is often not directly associated with adverse events in animal models, these studies have limited predictive power for the immunogenicity of the biologic in humans

It also modulates the nitric-oxide system, promoting nitric-oxide production in a dose-dependent way and countering agents that block the pathway [5]

Emerging studies on the molecular mechanisms of Ewing sarcoma hold promise for improvements in early detection, disease monitoring, lower treatment-related toxicity, overall survival and quality of life

This indicates a certain degree of functional redundancy within the vaginal ecosystem 39 and suggests that specific links exist between community composition and functional potential 78,79,80,81,82 (Table 1)