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By synthesizing current research advancements, the present review aims to provide new perspectives on the common pathological pathways underlying these diseases and to establish a theoretical foundation to guide the development of effective clinical interventions

As we expected, the overexpression of SIRT4 had a protective effect on AR42J cells when stimulated by L-Arg, with increased cell survival (Fig

P.MattilaJ

Dendritic cells (immune system cells that present antigens to T cells) expressing IDO can limit tryptophan supply to T cells in the extracellular matrix, thus limiting T-cell response to tumor growth [127]