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Future studies should focus on refining metabolictargeted therapies to improve tumor selectivity while minimizing systemic toxicity

Antioxid Redox Signal 11:703714 Akaike T, Ida T, Wei F-Y, Nishida M, Kumagai Y, Alam MM, Ihara H, Sawa T, Matsunaga T, Kasamatsu S, Nishimura A, Morita M, Tomizawa K, Nishimura A, Watanabe S, Inaba K, Shima H, Tanuma N, Jung M, Fujii S, Watanabe Y, Ohmuraya M, Nagy P, Feelisch M, Fukuto JM, Motohashi H (2017) Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

One patient treated with ETGBD experienced bleeding complication among 191 patients with bleeding tendency

Glutathione does not directly alter hormone levels